Korean aesthetic medicine has transformed the global skincare conversation. At the forefront of this movement are polynucleotide (PDRN) treatments — and their most celebrated form, Rejuran. At Dr. L'Art in London, these cutting-edge regenerative injections are available as part of a comprehensive approach to skin health.

What Are Polynucleotides (PDRN)?

Polynucleotides are long chains of nucleotides — the building blocks of DNA — derived from purified salmon DNA. When injected into the skin, they promote cellular regeneration, reduce inflammation, and stimulate fibroblast activity. The result is genuine skin repair at a cellular level.

Rejuran: The Korean Skin Healer

Rejuran Korean polynucleotides in London represent the gold standard in PDRN therapy. Originally developed in South Korea — where they have been used for over a decade — Rejuran treatments are now widely recognised as among the most effective skin regeneration options available globally.

What Does Rejuran Treat?

•        Fine lines and wrinkles from within

•        Acne scars and post-inflammatory hyperpigmentation

•        Enlarged pores

•        Skin laxity and loss of elasticity

•        Dehydrated, dull, or textured skin

•        Under-eye hollows and dark circles

Rejuran vs Profhilo: Understanding the Difference

Both Rejuran and Profhilo are injectable skin boosters that improve skin quality from within — but they work through different mechanisms.

Profhilo injections in London use an ultra-high concentration of hyaluronic acid to hydrate intensely and stimulate collagen and elastin production. It is exceptional for patients with dry, deflated, or crepe-like skin.

Rejuran, by contrast, works through DNA repair and cellular regeneration — particularly suited to patients with scarring, pigmentation, or skin that needs structural repair at a deeper level. Many patients benefit from both, and at Dr. L'Art a bespoke combination approach is often recommended.

Polynucleotide Injections for Acne Scar Removal

One of the most compelling applications of polynucleotides is in acne scar treatment. PDRN's regenerative properties accelerate tissue repair and collagen remodelling in scarred areas. Explore Rejuran polynucleotide injections in London for significant improvement in scar texture and depth over a course of sessions.

For deeper scarring, polynucleotides can be combined with microneedling in London or Ultrapulse CO2 laser treatment for enhanced results.

Juvelook and Lenisna: Next-Generation Skin Boosters

Alongside Rejuran, Dr. L'Art offers Juvelook and Lenisna treatments in London — injectable skin boosters combining hyaluronic acid with PDLLA microspheres that stimulate long-term collagen regeneration. These are excellent for patients seeking sustained skin quality improvements beyond the typical duration of standard fillers.

Biostimulators: The Broader Family

Polynucleotides sit within a broader family of biostimulator injections in London — treatments that stimulate the skin's own regenerative processes. Others include:

•        Sculptra in London — gradual collagen stimulator using poly-L-lactic acid

•        Radiesse in London — calcium hydroxylapatite for immediate volume and long-term stimulation

•        Ellanse in London — PCL-based filler with results lasting 1 to 4 years

Is Rejuran Right for You?

The ideal candidate for Rejuran and polynucleotide treatments is anyone experiencing skin quality concerns — from early ageing to textural damage, scarring, or chronic dehydration. To find out which regenerative treatment is right for your skin, book a consultation at Dr. L'Art Aesthetic Clinic — London's leading destination for Korean-inspired skin science.